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The Protein Structure Context of PolyQ Regions
Proteins containing glutamine repeats (polyQ) are known to be structurally unstable. Abnormal expansion of polyQ in some proteins exceeding a certain threshold leads to neurodegenerative disease, a symptom of which are protein aggregates. This has led to extensive research of the structure of polyQ...
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| 發表在: | PLoS One |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5268486/ https://ncbi.nlm.nih.gov/pubmed/28125688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170801 |
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