Inhibition of STAT3 by Anticancer Drug Bendamustine

Bendamustine (BENDA), which bears the bis(2-chloroethyl)amino moiety, is an alkylating agent that stops the growth of cancer cells by binding to DNA and interfering with its replication. However, the mechanism of action underlying its excellent clinical efficacy remains unclear. In this work, we rep...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Iwamoto, Kazunori, Uehara, Yutaka, Inoue, Yukie, Taguchi, Kyoko, Muraoka, Daisuke, Ogo, Naohisa, Matsuno, Kenji, Asai, Akira
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268383/
https://ncbi.nlm.nih.gov/pubmed/28125678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170709
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