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Inhibition of STAT3 by Anticancer Drug Bendamustine

Bendamustine (BENDA), which bears the bis(2-chloroethyl)amino moiety, is an alkylating agent that stops the growth of cancer cells by binding to DNA and interfering with its replication. However, the mechanism of action underlying its excellent clinical efficacy remains unclear. In this work, we rep...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Iwamoto, Kazunori, Uehara, Yutaka, Inoue, Yukie, Taguchi, Kyoko, Muraoka, Daisuke, Ogo, Naohisa, Matsuno, Kenji, Asai, Akira
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268383/
https://ncbi.nlm.nih.gov/pubmed/28125678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170709
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