Inhibition of STAT3 by Anticancer Drug Bendamustine

Bendamustine (BENDA), which bears the bis(2-chloroethyl)amino moiety, is an alkylating agent that stops the growth of cancer cells by binding to DNA and interfering with its replication. However, the mechanism of action underlying its excellent clinical efficacy remains unclear. In this work, we rep...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Iwamoto, Kazunori, Uehara, Yutaka, Inoue, Yukie, Taguchi, Kyoko, Muraoka, Daisuke, Ogo, Naohisa, Matsuno, Kenji, Asai, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268383/
https://ncbi.nlm.nih.gov/pubmed/28125678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170709
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