Загрузка...
Human LDL Receptor Enhances Sequestration of ApoE4 and VLDL Remnants on the Surface of Hepatocytes but Not Their Internalization in Mice
OBJECTIVE: In humans, apolipoprotein (apo) E4 is associated with elevated plasma cholesterol levels and a high risk of developing atherosclerosis, whereas apoE2 is protective. Here we investigate the mechanism by which mice expressing human apoE isoforms recapitulate this association when they also...
Сохранить в:
| Опубликовано в: : | Arterioscler Thromb Vasc Biol |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5268126/ https://ncbi.nlm.nih.gov/pubmed/18369154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.164863 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|