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Apo E structure determines VLDL clearance and atherosclerosis risk in mice

We have generated mice expressing the human apo E4 isoform in place of the endogenous murine apo E protein and have compared them with mice expressing the human apo E3 isoform. Plasma lipid and apolipoprotein levels in the mice expressing only the apo E4 isoform (4/4) did not differ significantly fr...

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Autores principales: Knouff, Christopher, Hinsdale, Myron E., Mezdour, Hafid, Altenburg, Michael K., Watanabe, Masahiko, Quarfordt, Steven H., Sullivan, Patrick M., Maeda, Nobuyo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC408371/
https://ncbi.nlm.nih.gov/pubmed/10359567
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