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Apolipoprotein E4 in Macrophages Enhances Atherogenesis in a Low Density Lipoprotein Receptor-dependent Manner(*)

Apolipoprotein E (apoE) and the low density lipoprotein receptor (LDLr) are well recognized determinants of atherosclerosis. In addition to hepatocytes, where both are highly expressed and contribute to plasma lipoprotein clearance, they are expressed in vascular cells and macrophages. In this study...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Altenburg, Michael, Johnson, Lance, Wilder, Jennifer, Maeda, Nobuyo
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278600/
https://ncbi.nlm.nih.gov/pubmed/17234631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M610712200
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