Loading...

The E Loop of the Transmitter Binding Site Is a Key Determinant of the Modulatory Effects of Physostigmine on Neuronal Nicotinic α4β2 Receptors

Physostigmine is a well known inhibitor of acetylcholinesterase, which can also activate, potentiate, and inhibit acetylcholine receptors, including neuronal nicotinic receptors comprising α4 and β2 subunits. We have found that the two stoichiometric forms of this receptor differ in the effects of p...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Pharmacol
Main Authors: Jin, Xiaochun, McCollum, Megan M., Germann, Allison L., Akk, Gustav, Steinbach, Joe Henry
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267520/
https://ncbi.nlm.nih.gov/pubmed/27895161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.106484
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!