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Functional Characterization of the α5(Asn398) Variant Associated with Risk for Nicotine Dependence in the α3β4α5 Nicotinic Receptor

Smoking is a major cause for premature death. Work aimed at identifying genetic factors that contribute to nicotine addiction has revealed several single nucleotide polymorphisms (SNPs) that are linked to smoking-related behaviors such as nicotine dependence and level of smoking. One of these SNPs l...

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Détails bibliographiques
Auteurs principaux: Li, Ping, McCollum, Megan, Bracamontes, John, Steinbach, Joe Henry, Akk, Gustav
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198915/
https://ncbi.nlm.nih.gov/pubmed/21856741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.073841
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