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Estimating and accounting for tumor purity in the analysis of DNA methylation data from cancer studies

We present a set of statistical methods for the analysis of DNA methylation microarray data, which account for tumor purity. These methods are an extension of our previously developed method for purity estimation; our updated method is flexible, efficient, and does not require data from reference sa...

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Pubblicato in:Genome Biol
Autori principali: Zheng, Xiaoqi, Zhang, Naiqian, Wu, Hua-Jun, Wu, Hao
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267453/
https://ncbi.nlm.nih.gov/pubmed/28122605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1143-5
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