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PEIS: a novel approach of tumor purity estimation by identifying information sites through integrating signal based on DNA methylation data

BACKGROUND: Tumor purity plays an important role in understanding the pathogenic mechanism of tumors. The purity of tumor samples is highly sensitive to tumor heterogeneity. Due to Intratumoral heterogeneity of genetic and epigenetic data, it is suitable to study the purity of tumors. Among them, th...

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Библиографические подробности
Опубликовано в: :BMC Bioinformatics
Главные авторы: Wang, Shudong, Wang, Lihua, Zhang, Yuanyuan, Pang, Shanchen, Wang, Xinzeng
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936156/
https://ncbi.nlm.nih.gov/pubmed/31888435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3227-1
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