Acute myeloid leukemia – strategies and challenges for targeting oncogenic Hedgehog/GLI signaling

Treatment of acute myeloid leukemia (AML), an aggressive and heterogeneous hematological malignancy, remains a challenge. Despite advances in our understanding of the complex genetics and biology of AML pathophysiology, these findings have been translated to the clinic with only limited success, and...

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Bibliografiske detaljer
Udgivet i:Cell Commun Signal
Main Authors: Aberger, Fritz, Hutterer, Evelyn, Sternberg, Christina, del Burgo, Pedro J., Hartmann, Tanja N.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267446/
https://ncbi.nlm.nih.gov/pubmed/28122581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-017-0163-4
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