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Acute myeloid leukemia – strategies and challenges for targeting oncogenic Hedgehog/GLI signaling
Treatment of acute myeloid leukemia (AML), an aggressive and heterogeneous hematological malignancy, remains a challenge. Despite advances in our understanding of the complex genetics and biology of AML pathophysiology, these findings have been translated to the clinic with only limited success, and...
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| Veröffentlicht in: | Cell Commun Signal |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5267446/ https://ncbi.nlm.nih.gov/pubmed/28122581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-017-0163-4 |
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