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Acute myeloid leukemia – strategies and challenges for targeting oncogenic Hedgehog/GLI signaling

Treatment of acute myeloid leukemia (AML), an aggressive and heterogeneous hematological malignancy, remains a challenge. Despite advances in our understanding of the complex genetics and biology of AML pathophysiology, these findings have been translated to the clinic with only limited success, and...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Aberger, Fritz, Hutterer, Evelyn, Sternberg, Christina, del Burgo, Pedro J., Hartmann, Tanja N.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267446/
https://ncbi.nlm.nih.gov/pubmed/28122581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-017-0163-4
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