IL-1β-Induced Accumulation of Amyloid: Macroautophagy in Skeletal Muscle Depends on ERK

The pathology of inclusion body myositis (IBM) involves an inflammatory response and β-amyloid deposits in muscle fibres. It is believed that MAP kinases such as the ERK signalling pathway mediate the inflammatory signalling in cells. Further, there is evidence that autophagic activity plays a cruci...

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Foilsithe in:Mediators Inflamm
Main Authors: Schmidt, Karsten, Wienken, Magdalena, Keller, Christian W., Balcarek, Peter, Münz, Christian, Schmidt, Jens
Formáid: Artigo
Teanga:Inglês
Foilsithe: Hindawi Publishing Corporation 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266815/
https://ncbi.nlm.nih.gov/pubmed/28167851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5470831
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