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Interrelation of inflammation and APP in sIBM: IL-1β induces accumulation of β-amyloid in skeletal muscle

Distinct interrelationships between inflammation and β-amyloid-associated degeneration, the two major hallmarks of the skeletal muscle pathology in sporadic inclusion body myositis (sIBM), have remained elusive. Expression of markers relevant for these pathomechanisms were analysed in biopsies of sI...

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Detalhes bibliográficos
Main Authors: Schmidt, Jens, Barthel, Konstanze, Wrede, Arne, Salajegheh, Mohammad, Bähr, Mathias, Dalakas, Marinos C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367696/
https://ncbi.nlm.nih.gov/pubmed/18420712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awn053
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