IL-1β-Induced Accumulation of Amyloid: Macroautophagy in Skeletal Muscle Depends on ERK

The pathology of inclusion body myositis (IBM) involves an inflammatory response and β-amyloid deposits in muscle fibres. It is believed that MAP kinases such as the ERK signalling pathway mediate the inflammatory signalling in cells. Further, there is evidence that autophagic activity plays a cruci...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mediators Inflamm
Prif Awduron: Schmidt, Karsten, Wienken, Magdalena, Keller, Christian W., Balcarek, Peter, Münz, Christian, Schmidt, Jens
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Hindawi Publishing Corporation 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266815/
https://ncbi.nlm.nih.gov/pubmed/28167851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5470831
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