TNF-α Induces Macroautophagy and Regulates MHC Class II Expression in Human Skeletal Muscle Cells

Macroautophagy, a homeostatic process that shuttles cytoplasmic constituents into endosomal and lysosomal compartments, has recently been shown to deliver antigens for presentation on major histocompatibility complex (MHC) class II molecules. Skeletal muscle fibers show a high level of constitutive...

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Autors principals: Keller, Christian W., Fokken, Claudia, Turville, Stuart G., Lünemann, Anna, Schmidt, Jens, Münz, Christian, Lünemann, Jan D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030397/
https://ncbi.nlm.nih.gov/pubmed/20980264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.159392
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