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Molecular treatment effects of alemtuzumab in skeletal muscles of patients with IBM

BACKGROUND: Mechanisms of inflammation and protein accumulation are crucial in inclusion body myositis (IBM). Recent evidence demonstrated that intravenous immunoglobulin failed to suppress cell-stress mediators in IBM. Here we studied the molecular changes in skeletal muscle biopsies from patients...

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Detalhes bibliográficos
Publicado no:BMC Neurol
Main Authors: Schmidt, Karsten, Kleinschnitz, Konstanze, Rakocevic, Goran, Dalakas, Marinos C., Schmidt, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833914/
https://ncbi.nlm.nih.gov/pubmed/27083892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12883-016-0568-5
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