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A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype–genotype association study

BACKGROUND: Western Cambodia is the epicentre of Plasmodium falciparum multidrug resistance and is facing high rates of dihydroartemisinin–piperaquine treatment failures. Genetic tools to detect the multidrug-resistant parasites are needed. Artemisinin resistance can be tracked using the K13 molecul...

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Detalhes bibliográficos
Publicado no:Lancet Infect Dis
Main Authors: Witkowski, Benoit, Duru, Valentine, Khim, Nimol, Ross, Leila S, Saintpierre, Benjamin, Beghain, Johann, Chy, Sophy, Kim, Saorin, Ke, Sopheakvatey, Kloeung, Nimol, Eam, Rotha, Khean, Chanra, Ken, Malen, Loch, Kaknika, Bouillon, Anthony, Domergue, Anais, Ma, Laurence, Bouchier, Christiane, Leang, Rithea, Huy, Rekol, Nuel, Grégory, Barale, Jean-Christophe, Legrand, Eric, Ringwald, Pascal, Fidock, David A, Mercereau-Puijalon, Odile, Ariey, Frédéric, Ménard, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science ;, The Lancet Pub. Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266792/
https://ncbi.nlm.nih.gov/pubmed/27818097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(16)30415-7
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