A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype–genotype association study

BACKGROUND: Western Cambodia is the epicentre of Plasmodium falciparum multidrug resistance and is facing high rates of dihydroartemisinin–piperaquine treatment failures. Genetic tools to detect the multidrug-resistant parasites are needed. Artemisinin resistance can be tracked using the K13 molecul...

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Опубликовано в: :Lancet Infect Dis
Главные авторы: Witkowski, Benoit, Duru, Valentine, Khim, Nimol, Ross, Leila S, Saintpierre, Benjamin, Beghain, Johann, Chy, Sophy, Kim, Saorin, Ke, Sopheakvatey, Kloeung, Nimol, Eam, Rotha, Khean, Chanra, Ken, Malen, Loch, Kaknika, Bouillon, Anthony, Domergue, Anais, Ma, Laurence, Bouchier, Christiane, Leang, Rithea, Huy, Rekol, Nuel, Grégory, Barale, Jean-Christophe, Legrand, Eric, Ringwald, Pascal, Fidock, David A, Mercereau-Puijalon, Odile, Ariey, Frédéric, Ménard, Didier
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier Science ;, The Lancet Pub. Group 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266792/
https://ncbi.nlm.nih.gov/pubmed/27818097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(16)30415-7
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