A novel field-based molecular assay to detect validated artemisinin-resistant k13 mutants

BACKGROUND: Given the risk of artemisinin resistance spreading from the Greater Mekong sub-region, prospective monitoring in sub-Saharan Africa should be expedited. Molecular biology techniques used for monitoring rely on the detection of k13 validated mutants by using PCR and Sanger sequencing appr...

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Bibliografske podrobnosti
izdano v:Malar J
Main Authors: Vachot-Ganée, Laurence, Khim, Nimol, Iannello, Alexandra, Legrand, Eric, Kim, Saorin, Eam, Rotha, Khean, Chanra, Ken, Malen, Ashley, Elizabeth, Tun, Kyaw Myo, Dhorda, Mehul, Nosten, François, Souleymane, Issa Mahamat, Blein, Sophie, Pachot, Alexandre, Ariey, Frédéric, Kaiser, Karine, Ménard, Didier
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916714/
https://ncbi.nlm.nih.gov/pubmed/29690890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-018-2329-y
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