The APOE ε4 genotype modulates CSF YKL-40 levels and their structural brain correlates in the continuum of Alzheimer's disease but not those of sTREM2

INTRODUCTION: Among other metabolic functions, the apolipoprotein E (APOE) plays a crucial role in neuroinflammation. We aimed at assessing whether APOE ε4 modulates levels of glial cerebrospinal fluid (CSF) biomarkers and their structural cerebral correlates along the continuum of Alzheimer's...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Alzheimers Dement (Amst)
Prif Awduron: Gispert, Juan Domingo, Monté, Gemma C., Suárez-Calvet, Marc, Falcon, Carles, Tucholka, Alan, Rojas, Santiago, Rami, Lorena, Sánchez-Valle, Raquel, Lladó, Albert, Kleinberger, Gernot, Haass, Christian, Molinuevo, José Luis
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2016
Pynciau:
PART II. State of the Field: Advances in Neuroimaging from the 2016 Alzheimer's Imaging Consortium
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266482/
https://ncbi.nlm.nih.gov/pubmed/28149943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2016.12.002
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