CSF glial biomarkers YKL40 and sTREM2 are associated with longitudinal volume and diffusivity changes in cognitively unimpaired individuals

Cerebrospinal fluid (CSF) YKL40 and sTREM2 are astroglial and microglial activity biomarkers, respectively. We assessed whether CSF YKL40 and sTREM2 baseline levels are associated with longitudinal brain volume and diffusivity changes in cognitively unimpaired adults. Two brain MRI scans of 36 parti...

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Detalhes bibliográficos
Publicado no:Neuroimage Clin
Main Authors: Falcon, Carles, Monté-Rubio, Gemma C., Grau-Rivera, Oriol, Suárez-Calvet, Marc, Sánchez-Valle, Raquel, Rami, Lorena, Bosch, Beatriz, Haass, Christian, Gispert, Juan Domingo, Molinuevo, José Luis
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458453/
https://ncbi.nlm.nih.gov/pubmed/30978656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2019.101801
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