CSF glial biomarkers YKL40 and sTREM2 are associated with longitudinal volume and diffusivity changes in cognitively unimpaired individuals

Cerebrospinal fluid (CSF) YKL40 and sTREM2 are astroglial and microglial activity biomarkers, respectively. We assessed whether CSF YKL40 and sTREM2 baseline levels are associated with longitudinal brain volume and diffusivity changes in cognitively unimpaired adults. Two brain MRI scans of 36 parti...

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Dettagli Bibliografici
Pubblicato in:Neuroimage Clin
Autori principali: Falcon, Carles, Monté-Rubio, Gemma C., Grau-Rivera, Oriol, Suárez-Calvet, Marc, Sánchez-Valle, Raquel, Rami, Lorena, Bosch, Beatriz, Haass, Christian, Gispert, Juan Domingo, Molinuevo, José Luis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
Soggetti:
Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458453/
https://ncbi.nlm.nih.gov/pubmed/30978656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2019.101801
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