Decreased platelet responsiveness to clopidogrel correlates with CYP2C19 and PON1 polymorphisms in atherosclerotic patients

Clopidogrel and aspirin are the most commonly used medications worldwide for dual antiplatelet therapy after percutaneous coronary intervention. However, clopidogrel hyporesponsiveness related to gene polymorphisms is a concern. Populations with higher degrees of genetic admixture may have increased...

詳細記述

保存先:
書誌詳細
出版年:Braz J Med Biol Res
主要な著者: Marchini, J.F.M., Pinto, M.R., Novaes, G.C., Badran, A.V., Pavão, R.B., Figueiredo, G.L., Lago, I.M., Lima-Filho, M.O., Lemos, D.C., Tonani, M., Antloga, C.M., Oliveira, L., Lorenzi, J.C., Marin-Neto, J.A.
フォーマット: Artigo
言語:Inglês
出版事項: Associação Brasileira de Divulgação Científica 2017
主題:
Clinical Investigation
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264542/
https://ncbi.nlm.nih.gov/pubmed/28076455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20165660
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