Decreased platelet responsiveness to clopidogrel correlates with CYP2C19 and PON1 polymorphisms in atherosclerotic patients

Clopidogrel and aspirin are the most commonly used medications worldwide for dual antiplatelet therapy after percutaneous coronary intervention. However, clopidogrel hyporesponsiveness related to gene polymorphisms is a concern. Populations with higher degrees of genetic admixture may have increased...

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Detaylı Bibliyografya
Yayımlandı:Braz J Med Biol Res
Asıl Yazarlar: Marchini, J.F.M., Pinto, M.R., Novaes, G.C., Badran, A.V., Pavão, R.B., Figueiredo, G.L., Lago, I.M., Lima-Filho, M.O., Lemos, D.C., Tonani, M., Antloga, C.M., Oliveira, L., Lorenzi, J.C., Marin-Neto, J.A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Associação Brasileira de Divulgação Científica 2017
Konular:
Clinical Investigation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264542/
https://ncbi.nlm.nih.gov/pubmed/28076455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20165660
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