Decreased platelet responsiveness to clopidogrel correlates with CYP2C19 and PON1 polymorphisms in atherosclerotic patients

Clopidogrel and aspirin are the most commonly used medications worldwide for dual antiplatelet therapy after percutaneous coronary intervention. However, clopidogrel hyporesponsiveness related to gene polymorphisms is a concern. Populations with higher degrees of genetic admixture may have increased...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Braz J Med Biol Res
Egile Nagusiak: Marchini, J.F.M., Pinto, M.R., Novaes, G.C., Badran, A.V., Pavão, R.B., Figueiredo, G.L., Lago, I.M., Lima-Filho, M.O., Lemos, D.C., Tonani, M., Antloga, C.M., Oliveira, L., Lorenzi, J.C., Marin-Neto, J.A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Associação Brasileira de Divulgação Científica 2017
Gaiak:
Clinical Investigation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264542/
https://ncbi.nlm.nih.gov/pubmed/28076455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20165660
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