Targeting EP4 downstream c‐Jun through ERK1/2‐mediated reduction of DNMT1 reveals novel mechanism of solamargine‐inhibited growth of lung cancer cells

Lung cancer is the most common cancer and the leading cause of cancer deaths worldwide. We previously showed that solamargine, one natural phytochemicals from traditional plants, inhibited the growth of lung cancer cells through inhibition of prostaglandin E2 (PGE (2)) receptor EP4. However, the pot...

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Bibliografische gegevens
Gepubliceerd in:J Cell Mol Med
Hoofdauteurs: Chen, Yuqing, Tang, Qing, Xiao, Qian, Yang, LiJun, Hann, Swei S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264151/
https://ncbi.nlm.nih.gov/pubmed/27620163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12958
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