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The enhancement of combination of berberine and metformin in inhibition of DNMT1 gene expression through interplay of SP1 and PDPK1

Berberine (BBR), one of active alkaloid found in the rhizome, exhibited anti‐cancer properties. We have showed that BBR inhibited growth of non‐small cell lung cancer (NSCLC) cells through mitogen‐activated protein kinase (MAPK)‐mediated increase in forkhead box O3a (FOXO3a). However, the in‐depth m...

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Dades bibliogràfiques
Publicat a:J Cell Mol Med
Autors principals: Zheng, Fang, Wu, JingJing, Tang, Qing, Xiao, Qian, Wu, WanYin, Hann, Swei Sunny
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742731/
https://ncbi.nlm.nih.gov/pubmed/28840963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13347
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