The enhancement of combination of berberine and metformin in inhibition of DNMT1 gene expression through interplay of SP1 and PDPK1

Berberine (BBR), one of active alkaloid found in the rhizome, exhibited anti‐cancer properties. We have showed that BBR inhibited growth of non‐small cell lung cancer (NSCLC) cells through mitogen‐activated protein kinase (MAPK)‐mediated increase in forkhead box O3a (FOXO3a). However, the in‐depth m...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zheng, Fang, Wu, JingJing, Tang, Qing, Xiao, Qian, Wu, WanYin, Hann, Swei Sunny
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742731/
https://ncbi.nlm.nih.gov/pubmed/28840963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13347
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