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Metal-Assisted Oxo Atom Addition to an Fe(III) Thiolate

Cysteinate oxygenation is intimately tied to the function of both cysteine dioxygenases (CDOs) and nitrile hydratases (NHases), and yet the mechanisms by which sulfurs are oxidized by these enzymes are unknown, in part because intermediates have yet to be observed. Herein, we report a five-coordinat...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Villar-Acevedo, Gloria, Lugo-Mas, Priscilla, Blakely, Maike N., Rees, Julian A., Ganas, Abbie S., Hanada, Erin M., Kaminsky, Werner, Kovacs, Julie A
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5262503/
https://ncbi.nlm.nih.gov/pubmed/28033001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b03512
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