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How Does Single Oxygen Atom Addition Affect the Properties of an Fe–Nitrile Hydratase Analogue? The Compensatory Role of the Unmodified Thiolate

Nitrile hydratase (NHase) is one of a growing number of enzymes shown to contain post-translationally modified cysteine sulfenic acids (Cys-SOH). Cysteine sulfenic acids have been shown to play diverse roles in cellular processes, including transcriptional regulation, signal transduction, and the re...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Lugo-Mas, Priscilla, Dey, Abhishek, Xu, Liang, Davin, Steven D., Benedict, Jason, Kaminsky, Werner, Hodgson, Keith O., Hedman, Britt, Solomon, Edward I., Kovacs, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481871/
https://ncbi.nlm.nih.gov/pubmed/16925440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja062706k
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