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A molecular mechanism of chaperone-client recognition

Molecular chaperones are essential in aiding client proteins to fold into their native structure and in maintaining cellular protein homeostasis. However, mechanistic aspects of chaperone function are still not well understood at the atomic level. We use nuclear magnetic resonance spectroscopy to el...

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Publicado en:Sci Adv
Autores principales: He, Lichun, Sharpe, Timothy, Mazur, Adam, Hiller, Sebastian
Formato: Artigo
Lenguaje:Inglês
Publicado: American Association for the Advancement of Science 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5262456/
https://ncbi.nlm.nih.gov/pubmed/28138538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1601625
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