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A molecular mechanism of chaperone-client recognition

Molecular chaperones are essential in aiding client proteins to fold into their native structure and in maintaining cellular protein homeostasis. However, mechanistic aspects of chaperone function are still not well understood at the atomic level. We use nuclear magnetic resonance spectroscopy to el...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: He, Lichun, Sharpe, Timothy, Mazur, Adam, Hiller, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5262456/
https://ncbi.nlm.nih.gov/pubmed/28138538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1601625
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