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Molecular Chaperones Accelerate the Evolution of Their Protein Clients in Yeast

Protein stability is a major constraint on protein evolution. Molecular chaperones, also known as heat-shock proteins, can relax this constraint and promote protein evolution by diminishing the deleterious effect of mutations on protein stability and folding. This effect, however, has only been stab...

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Detalhes bibliográficos
Publicado no:Genome Biol Evol
Main Authors: Alvarez-Ponce, David, Aguilar-Rodríguez, José, Fares, Mario A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735891/
https://ncbi.nlm.nih.gov/pubmed/31297528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evz147
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