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A molecular mechanism of chaperone-client recognition

Molecular chaperones are essential in aiding client proteins to fold into their native structure and in maintaining cellular protein homeostasis. However, mechanistic aspects of chaperone function are still not well understood at the atomic level. We use nuclear magnetic resonance spectroscopy to el...

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Veröffentlicht in:Sci Adv
Hauptverfasser: He, Lichun, Sharpe, Timothy, Mazur, Adam, Hiller, Sebastian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5262456/
https://ncbi.nlm.nih.gov/pubmed/28138538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1601625
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