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The activation loop of PIP5K functions as a membrane sensor essential for lipid substrate processing
Phosphatidylinositol 4-phosphate 5-kinase (PIP5K), a representative member of the phosphatidylinositol phosphate kinase (PIPK) family, is a major enzyme that biosynthesizes the signaling molecule PI(4,5)P(2) (phosphatidylinositol 4,5-bisphosphate) in eukaryotic cells. The stringent specificity towar...
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| Publicado no: | Sci Adv |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5262455/ https://ncbi.nlm.nih.gov/pubmed/28138522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1600925 |
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