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Removal of phospho-head groups of membrane lipids immobilizes voltage sensors of K(+) channels
A fundamental question regarding the gating mechanism of voltage-activated K(+) (Kv) channels is how five positively charged voltage-sensing residues in the fourth transmembrane (TM) segment(1, 2) are energetically stabilized, as they operate in a low-dielectric cell membrane. The simplest solution...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4026191/ https://ncbi.nlm.nih.gov/pubmed/18273018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06618 |
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