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Energetic role of the paddle motif in voltage gating of Shaker K(+) channels
Voltage-gated ion channels underlie rapid electric signaling in excitable cells. Electrophysiological studies have established that the N-terminal half of the fourth transmembrane segment ((NT)S4) of these channels functions as the primary voltage sensor, whereas crystallographic studies have shown...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3777420/ https://ncbi.nlm.nih.gov/pubmed/23542156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2535 |
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