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Energetic role of the paddle motif in voltage gating of Shaker K(+) channels

Voltage-gated ion channels underlie rapid electric signaling in excitable cells. Electrophysiological studies have established that the N-terminal half of the fourth transmembrane segment ((NT)S4) of these channels functions as the primary voltage sensor, whereas crystallographic studies have shown...

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Autori principali: Xu, Yanping, Ramu, Yajamana, Shin, Hyeon-Gyu, Yamakaze, Jayden, Lu, Zhe
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777420/
https://ncbi.nlm.nih.gov/pubmed/23542156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2535
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