Therapeutic advantage of pro-electrophilic drugs to activate the Nrf2/ARE pathway in Alzheimer's disease models

Alzheimer's disease (AD) is characterized by synaptic and neuronal loss, which occurs at least partially through oxidative stress induced by oligomeric amyloid-β (Aβ)-peptide. Carnosic acid (CA), a chemical found in rosemary and sage, is a pro-electrophilic compound that is converted to its act...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Lipton, Stuart A, Rezaie, Tayebeh, Nutter, Anthony, Lopez, Kevin M, Parker, James, Kosaka, Kunio, Satoh, Takumi, McKercher, Scott R, Masliah, Eliezer, Nakanishi, Nobuki
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261011/
https://ncbi.nlm.nih.gov/pubmed/27906174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.389
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars