Protective Effect of Carnosic Acid, a Pro-Electrophilic Compound, in Models of Oxidative Stress and Light-Induced Retinal Degeneration

PURPOSE. The herb rosemary has been reported to have antioxidant and anti-inflammatory activity. We have previously shown that carnosic acid (CA), present in rosemary extract, crosses the blood–brain barrier to exert neuroprotective effects by upregulating endogenous antioxidant enzymes via the Nrf2...

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Detalhes bibliográficos
Main Authors: Rezaie, Tayebeh, McKercher, Scott R., Kosaka, Kunio, Seki, Masaaki, Wheeler, Larry, Viswanath, Veena, Chun, Teresa, Joshi, Rabina, Valencia, Marcos, Sasaki, Shunsuke, Tozawa, Terumasa, Satoh, Takumi, Lipton, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508754/
https://ncbi.nlm.nih.gov/pubmed/23081978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10793
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