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Tissue-type plasminogen activator controls neuronal death by raising surface dynamics of extrasynaptic NMDA receptors

N-methyl-d-aspartate receptors (NMDARs) are ion channels whose synaptic versus extrasynaptic localization critically influences their functions. This distribution of NMDARs is highly dependent on their lateral diffusion at the cell membrane. Each obligatory subunit of NMDARs (GluN1 and GluN2) contai...

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Библиографические подробности
Опубликовано в: :Cell Death Dis
Главные авторы: Lesept, Flavie, Chevilley, Arnaud, Jezequel, Julie, Ladépêche, Laurent, Macrez, Richard, Aimable, Margaux, Lenoir, Sophie, Bertrand, Thomas, Rubrecht, Laëtitia, Galea, Pascale, Lebouvier, Laurent, Petersen, Karl-Uwe, Hommet, Yannick, Maubert, Eric, Ali, Carine, Groc, Laurent, Vivien, Denis
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260909/
https://ncbi.nlm.nih.gov/pubmed/27831563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.279
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