Tissue-type plasminogen activator controls neuronal death by raising surface dynamics of extrasynaptic NMDA receptors

N-methyl-d-aspartate receptors (NMDARs) are ion channels whose synaptic versus extrasynaptic localization critically influences their functions. This distribution of NMDARs is highly dependent on their lateral diffusion at the cell membrane. Each obligatory subunit of NMDARs (GluN1 and GluN2) contai...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Lesept, Flavie, Chevilley, Arnaud, Jezequel, Julie, Ladépêche, Laurent, Macrez, Richard, Aimable, Margaux, Lenoir, Sophie, Bertrand, Thomas, Rubrecht, Laëtitia, Galea, Pascale, Lebouvier, Laurent, Petersen, Karl-Uwe, Hommet, Yannick, Maubert, Eric, Ali, Carine, Groc, Laurent, Vivien, Denis
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260909/
https://ncbi.nlm.nih.gov/pubmed/27831563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.279
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