Tissue-type plasminogen activator controls neuronal death by raising surface dynamics of extrasynaptic NMDA receptors

N-methyl-d-aspartate receptors (NMDARs) are ion channels whose synaptic versus extrasynaptic localization critically influences their functions. This distribution of NMDARs is highly dependent on their lateral diffusion at the cell membrane. Each obligatory subunit of NMDARs (GluN1 and GluN2) contai...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Lesept, Flavie, Chevilley, Arnaud, Jezequel, Julie, Ladépêche, Laurent, Macrez, Richard, Aimable, Margaux, Lenoir, Sophie, Bertrand, Thomas, Rubrecht, Laëtitia, Galea, Pascale, Lebouvier, Laurent, Petersen, Karl-Uwe, Hommet, Yannick, Maubert, Eric, Ali, Carine, Groc, Laurent, Vivien, Denis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260909/
https://ncbi.nlm.nih.gov/pubmed/27831563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.279
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