Tissue-type plasminogen activator controls neuronal death by raising surface dynamics of extrasynaptic NMDA receptors

N-methyl-d-aspartate receptors (NMDARs) are ion channels whose synaptic versus extrasynaptic localization critically influences their functions. This distribution of NMDARs is highly dependent on their lateral diffusion at the cell membrane. Each obligatory subunit of NMDARs (GluN1 and GluN2) contai...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Lesept, Flavie, Chevilley, Arnaud, Jezequel, Julie, Ladépêche, Laurent, Macrez, Richard, Aimable, Margaux, Lenoir, Sophie, Bertrand, Thomas, Rubrecht, Laëtitia, Galea, Pascale, Lebouvier, Laurent, Petersen, Karl-Uwe, Hommet, Yannick, Maubert, Eric, Ali, Carine, Groc, Laurent, Vivien, Denis
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260909/
https://ncbi.nlm.nih.gov/pubmed/27831563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.279
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