Selective inhibition of GluN2D-containing N-methyl-D-aspartate receptors prevents tissue plasminogen activator-promoted neurotoxicity both in vitro and in vivo

BACKGROUND: Tissue plasminogen activator (tPA) exerts multiple functions in the central nervous system, depending on the partner with which it interacts. In particular, tPA acts as a positive neuromodulator of N-methyl-D-aspartate glutamatergic receptors (NMDAR). At the molecular level, it has been...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jullienne, Amandine, Montagne, Axel, Orset, Cyrille, Lesept, Flavie, Jane, David E, Monaghan, Daniel T, Maubert, Eric, Vivien, Denis, Ali, Carine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204249/
https://ncbi.nlm.nih.gov/pubmed/21975018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-68
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados