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ER stress inhibitor attenuates hearing loss and hair cell death in Cdh23(erl/erl) mutant mice

Hearing loss is one of the most common sensory impairments in humans. Mouse mutant models helped us to better understand the mechanisms of hearing loss. Recently, we have discovered that the erlong (erl) mutation of the cadherin23 (Cdh23) gene leads to hearing loss due to hair cell apoptosis. In thi...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Hu, Juan, Li, Bo, Apisa, Luke, Yu, Heping, Entenman, Shami, Xu, Min, Stepanyan, Ruben, Guan, Bo-Jhih, Müller, Ulrich, Hatzoglou, Maria, Zheng, Qing Yin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260868/
https://ncbi.nlm.nih.gov/pubmed/27882946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.386
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