ER stress inhibitor attenuates hearing loss and hair cell death in Cdh23(erl/erl) mutant mice

Hearing loss is one of the most common sensory impairments in humans. Mouse mutant models helped us to better understand the mechanisms of hearing loss. Recently, we have discovered that the erlong (erl) mutation of the cadherin23 (Cdh23) gene leads to hearing loss due to hair cell apoptosis. In thi...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Hu, Juan, Li, Bo, Apisa, Luke, Yu, Heping, Entenman, Shami, Xu, Min, Stepanyan, Ruben, Guan, Bo-Jhih, Müller, Ulrich, Hatzoglou, Maria, Zheng, Qing Yin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260868/
https://ncbi.nlm.nih.gov/pubmed/27882946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.386
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