ER stress inhibitor attenuates hearing loss and hair cell death in Cdh23(erl/erl) mutant mice

Hearing loss is one of the most common sensory impairments in humans. Mouse mutant models helped us to better understand the mechanisms of hearing loss. Recently, we have discovered that the erlong (erl) mutation of the cadherin23 (Cdh23) gene leads to hearing loss due to hair cell apoptosis. In thi...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Hu, Juan, Li, Bo, Apisa, Luke, Yu, Heping, Entenman, Shami, Xu, Min, Stepanyan, Ruben, Guan, Bo-Jhih, Müller, Ulrich, Hatzoglou, Maria, Zheng, Qing Yin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260868/
https://ncbi.nlm.nih.gov/pubmed/27882946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.386
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