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N-Heterocyclic Carbene Gold(I) Complexes Conjugated to a Leukemia Specific DNA-Aptamer for Targeted Drug Delivery
This report describes the synthesis and characterization of novel N-heterocyclic carbene (NHC) gold(I) complexes and their bioconjugation to the CCRF-CEM leukemia specific aptamer sgc8c. Confirmation of successful bioconjugation was achieved by using fluorescent tags on both the NHC-Au(I) complex an...
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| Publicado en: | Angew Chem Int Ed Engl |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5260866/ https://ncbi.nlm.nih.gov/pubmed/27311814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201602702 |
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