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Aptamer-Mediated Selective Delivery of a Cytotoxic Cationic NHC-Au(I) Complex to Cancer Cells
A novel cationic NHC-Au(I) complex was synthesized and studied for its antitumor activity. For all the cell lines tested, cationic NHC-Au(I) complex 2 shows much higher cytotoxicity than its neutral analogue 1. To achieve selective cancer cell targeting, complex 2 was covalently conjugated to aptame...
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| Publicado no: | Dalton Trans |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5736135/ https://ncbi.nlm.nih.gov/pubmed/29192701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7dt02616a |
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