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N-Heterocyclic Carbene-Catalyzed Conjugate Additions of Alcohols

An efficient intermolecular conjugate addition of alcohols to activated alkenes catalyzed by N-heterocyclic carbenes has been developed. With 5 mol % of the free carbene derived from IMes•HCl, unsaturated ketones and esters are competent substrates and a variety of primary and secondary alcohols can...

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Detalhes bibliográficos
Main Authors: Phillips, Eric M., Riedrich, Matthias, Scheidt, Karl A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944903/
https://ncbi.nlm.nih.gov/pubmed/20809579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1061196
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