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N-Heterocyclic Carbene-Catalyzed Conjugate Additions of Alcohols
An efficient intermolecular conjugate addition of alcohols to activated alkenes catalyzed by N-heterocyclic carbenes has been developed. With 5 mol % of the free carbene derived from IMes•HCl, unsaturated ketones and esters are competent substrates and a variety of primary and secondary alcohols can...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2944903/ https://ncbi.nlm.nih.gov/pubmed/20809579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1061196 |
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