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N-Heterocyclic Carbene-Catalyzed Enantioselective Mannich Reactions with α-Aryloxyacetaldehydes

[Image: see text] N-Heterocyclic carbenes (NHCs) catalyze a new Mannich-type reaction to form β-amino acid derivatives in high yield and enantioselectivity. The reaction is initiated by the addition of an NHC to an α-aryloxyaldehyde followed by elimination of a phenoxide anion which generates an eno...

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Bibliografiset tiedot
Päätekijät: Kawanaka, Yasufumi, Phillips, Eric M., Scheidt, Karl A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836487/
https://ncbi.nlm.nih.gov/pubmed/20000857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9094044
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