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A role for proteinase-activated receptor–1 in inflammatory bowel diseases

Proteinase-activated receptor–1 (PAR(1)), a G protein–coupled receptor activated by thrombin, is highly expressed in different cell types of the gastrointestinal tract. The activity of thrombin and of other proteinases is significantly increased in the colon of inflammatory bowel disease (IBD) patie...

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書誌詳細
主要な著者: Vergnolle, Nathalie, Cellars, Laurie, Mencarelli, Andrea, Rizzo, Giovanni, Swaminathan, Sunita, Beck, Paul, Steinhoff, Martin, Andrade-Gordon, Patricia, Bunnett, Nigel W., Hollenberg, Morley D., Wallace, John L., Cirino, Giuseppe, Fiorucci, Stefano
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC526028/
https://ncbi.nlm.nih.gov/pubmed/15545995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421689
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